Carbon monoxide (CO) is a colorless, odourless, and tasteless gas that is slightly less dense than air. CO is toxic to humans as it binds to hemoglobin and thereby limits O2 transport to organs. A HbCO level of over 50% may result in seizure, coma, and fatality. (Link)
Hence, use of the Detalo devices contains risk of death, fire, bacterial infection and similar. Therefore, safety instructions and precautions should carefully be adhered to.
Using a Detalo device, HbCO levels rise from 0.5%-1.5% in non-smoking patients to between 2.5% and 9% depending on the dose. In comparison, studies have demonstrated that smoking cigarettes may raise HbCO levels up to 20-30% (link) WHO has a set of guidelines for carbon monoxide listed here.
The Detalo devices have been designed to minimize intoxication risks as much as possible:
- A safety controller monitors the operation of valves and functionality at all times.
- The period that valves are open to let in CO is limited to a maximum of 7 seconds
- A manual button placed on the side of the Detalo which when pressed initiates a comprehensive testing function of all vital functioning must be activated before any CO may be administrated.
- A separate security controller ensures safety in the Detalo hardware.
Strict guidelines increase safety:
- The main CO source must be closed at all times a patient is connected to the blood volume analyzer.
- The device must be inspected for damages or signs of wear and tear on a weekly basis.
- The CO source must not contain more than 30 liters of pure (99.997%) CO.
- Only 1-2 measurement must be performed per patient per 24 hours.
- CO-rebreathing devices should not be used with children or pregnant woman
Informational purposes only. See instructions for all details. In case of inconsistencies, the manual always overrules description on this page.